Who should not use Sancuso?

  • Do not use Sancuso if you are allergic to granisetron or any of the other ingredients in Sancuso.

What should I tell my healthcare provider before using Sancuso?

  • Tell your healthcare provider about all your medical conditions, including if you:
    • if you are allergic to medical adhesive tape, adhesive dressings, or other skin patches
    • have pain or swelling in stomach area (abdomen).
    • are pregnant. It is not known if Sancuso will harm your unborn baby. Talk to your healthcare provider if you are pregnant or plan to become pregnant.
    • are breastfeeding, or plan to breastfeed. It is not known if Sancuso passes into your breast milk.
  • Tell your healthcare professional about all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements. Other medicines may affect how Sancuso works. Sancuso may also affect how other medicines work.

How should Sancuso be used?
Use Sancuso exactly as prescribed. See the detailed Patient Instructions for Applying Sancuso in the Patient Information leaflet.

What should I avoid while using Sancuso?

  • Do not apply any heat source over or near the Sancuso patch. For example,
    • a heating pad or heat lamp should not be used where the patch is applied.
    • You should also avoid extended exposure to heat as it may increase your granisetron blood levels during the time of heat exposure.
  • Avoid sunlight. The medicine in Sancuso (granisetron) may not work well and/or may affect your skin if exposed to direct sunlight and the light from sunlamps or tanning beds.
    • While wearing the patch keep it covered with clothing if you will be in sunlight or near a sunlamp, including tanning beds.
    • Keep the skin where Sancuso was applied covered for another 10 days after the patch is taken off to protect from exposure to direct sunlight.

What are the possible side effects of Sancuso?

  • Sancuso can cause serious side effects:
    • Using Sancuso may make it harder to identify certain stomach and bowel problems that are from other causes. Tell your healthcare provider if you have any stomach area (abdominal) pain or swelling while using Sancuso.
    • Skin reactions. Skin reactions can happen just at the patch application site or outside the patch application site. Tell your healthcare provider if you get any redness, rashes, bumps, blisters or itching at the patch application site, and especially if they spread outside the place where the patch was or if they appear outside the patch application site. You may need to stop using Sancuso.
    • You may see mild redness on the skin where the patch is removed. This redness should go away within three days. If redness continues, tell your healthcare professional.
  • The most common side effect of Sancuso is constipation.
  • This is not the only possible side effect of Sancuso. Tell your healthcare professional if you have any side effect that bothers you or that does not go away.
  • Sancuso is a prescription medicine used to prevent nausea and vomiting in people receiving some types of chemotherapy treatment.
  • For more information, ask your healthcare professional or pharmacist.
  • To report suspected side effects, contact Kyowa Kirin, Inc. at 1-800-SANCUSO or FDA at 1-800-FDA-1088 or: WWW.FDA.GOV/MEDWATCH.