How to use SANCUSO® (granisetron transdermal system)
Before starting SANCUSO
Tell your healthcare professional about all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements. Some of them may affect how SANCUSO works or how your other medicines work.
Be sure to keep the patch inside the sealed pouch until you are ready to apply it
Do not cut the SANCUSO patch into pieces
Apply SANCUSO a minimum of 24 to a maximum of 48 hours before your scheduled chemotherapy treatment
Apply SANCUSO to a clean, dry, healthy area of skin on the outside part of your upper arm. Do not put SANCUSO on areas that have been treated with creams, oils, lotions, powders, or other skincare products that might keep the patch from sticking to your skin. SANCUSO should not be placed on skin that is red, irritated, or damaged
If the patch does not stick well, you may use surgical bandages or medical adhesive tape to keep the patch in place. Place tape or bandages on the edges of the patch. Do not completely cover the patch with bandages or tape and do not wrap completely around your arm. If the patch comes more than half off or it becomes damaged see your healthcare provider
If you’ve attached your patch and your chemotherapy is delayed or canceled, or if the patch completely falls off, the SANCUSO Patch Replacement Program may be able to help you get a replacement patch
Watch as an oncology nurse reviews the simple steps to apply the SANCUSO patch.
Follow these steps for proper application
Remove the patch from the carton; tear the pouch open and remove the patch. Each pouch contains 1 SANCUSO patch stuck onto a rigid plastic film, and a separate clear protective liner.
Remove the thin, clear protective liner to expose the printed side of the patch.
Bend the patch in the middle and remove one half of the rigid plastic film. Be careful not to stick the patch to itself and avoid touching the sticky side of the patch.
While holding the remaining half of the rigid plastic film, apply the patch to the skin. Remove the second half of the rigid plastic film and press the whole patch firmly in place with your fingers and smooth down. Press firmly making sure it sticks well, especially around the edges.
Wash your hands right away after applying the patch to remove any medicine that might have stuck to your fingers.
Keep the patch in place for the duration of the chemotherapy. Remove the patch at least 1 day (24 hours) after chemotherapy is finished. The patch can be worn up to 7 days, depending on the number of days your chemotherapy treatment lasts.
Avoid sunlight. The medicine in SANCUSO may not work as well and/or may affect your skin if exposed to direct sunlight or the light from sunlamps or tanning beds. While you are wearing SANCUSO, you must keep it covered (ie, under clothing) if there is a risk of exposure to sunlight or sunlamps. Continue to keep the application area covered for 10 days after removing SANCUSO
Showering or bathing will not change the way that SANCUSO works—however, you should try to avoid immersing SANCUSO in water for long periods of time to prevent the patch from coming off
Because there is no information on the effect of swimming, strenuous exercise, or use of a sauna or whirlpool on the patch, you should also avoid these activities while wearing SANCUSO
When not to use SANCUSO
Avoid use if you are allergic to granisetron or any of the other ingredients in SANCUSO, or if you have allergies to medical adhesive tape, adhesive dressings, or other skin patches
Avoid use if you are pregnant or breastfeeding unless your healthcare professional has told you that you can use it. Be sure to tell your healthcare professional if you are pregnant, if you become pregnant, or plan to become pregnant while using SANCUSO, or if you are planning to breastfeed or are breastfeeding
Possible side effects of SANCUSO
SANCUSO can cause side effects in some patients. The most common side effects with SANCUSO are constipation and headache
Be sure to notify your healthcare professional if you have pain in your abdomen or your abdomen becomes swollen
While you are wearing SANCUSO, you may see some mild redness at or around the patch application site. If uncomfortable irritation or excessive itchiness occurs, remove the patch and call your healthcare professional
Indication and Important Safety Information For Patients
SANCUSO® (granisetron transdermal system) is indicated for the prevention of nausea and vomiting in patients receiving moderately and/or highly emetogenic chemotherapy regimens of up to 5 consecutive days duration.
IMPORTANT SAFETY INFORMATION FOR PATIENTS
What is SANCUSO® (granisetron transdermal system)?
SANCUSO is a prescription medicine used to prevent nausea and vomiting in patients receiving some types of chemotherapy treatment. SANCUSO is a skin patch that slowly releases the medicine contained in the adhesive (glue), through clean and intact skin areas into your bloodstream while you wear the patch. SANCUSO is for skin use only.
Who should not use SANCUSO?
Do not use SANCUSO if you are allergic to granisetron or any of the other ingredients in SANCUSO.
What should I tell my healthcare provider before using SANCUSO?
Tell your healthcare provider about all your medical conditions, including if you:
Are allergic to medical adhesive tape, adhesive dressings or other skin patches.
Have pain or swelling in your stomach area (abdomen).
Are pregnant or plan to become pregnant. It is not known if SANCUSO will harm your unborn baby.
Are breast-feeding or plan to breastfeed. It is not known if SANCUSO passes into your breast milk.
Tell your healthcare provider about all the medicines you take,
including prescription and non-prescription medicines, vitamins and herbal supplements. Other medicines may affect how SANCUSO works. SANCUSO may also affect how other medicines work.
What should I avoid while using SANCUSO?
Do not apply any heat source over or near the SANCUSO patch
as it may increase your blood levels during the time of heat exposure.
The medicine in SANCUSO (granisetron) may not work as well and/or may affect your skin if exposed to direct sunlight or the light from sunlamps.
Keep the patch covered with clothing if you will be in sunlight or near a sunlamp.
Keep the skin where SANCUSO was applied covered for another 10 days after the patch is taken off.
What are the possible side effects of SANCUSO?
SANCUSO can cause serious side effects:
Using SANCUSO may make it harder to identify certain stomach and bowel problems that are from other causes.
Tell your healthcare provider if you have any stomach area (abdominal) pain or swelling while using SANCUSO.
Tell your healthcare provider if you experience any redness, rashes, bumps, blisters or itching at the patch application site, and especially if they spread or appear outside the patch application site. You may need to stop using SANCUSO.
The most common side effect of SANCUSO is constipation.
These are not all the possible side effects of SANCUSO. Tell your healthcare provider if you have any side effect that bothers you or that does not go away.
For more information, ask your healthcare provider or pharmacist.