Important Safety Information Patient Information This website is intended for US residents only.
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What is SANCUSO®
(granisetron transdermal system)?

What makes SANCUSO different?

Sancuso patient brochure
See SANCUSO patient brochure

Is SANCUSO right for me?

Sancuso questionnaire
  • Ask your healthcare professional if SANCUSO might be right for you
  • Some patients treated for cancer experience difficulty swallowing pills, feel nauseated, and are unable to keep pills down. This can be caused by certain cancers or certain cancer treatments that may make it hard for you to swallow medicine that prevents CINV
  • Some cancer treatments may also reduce the ability of your intestines to absorb or retain the medicine in pills or tablets
  • Because SANCUSO is a skin patch that enters your system through your skin rather than an oral medication, it might be the right choice for patients who have trouble swallowing or keeping down pills, and those with the reduced ability to absorb or retain medicine in their intestines

See SANCUSO questionnaire


How does SANCUSO prevent CINV?

How CINV starts

Chemotherapy may irritate cells in the small intestine and/or the brain

Some chemotherapy may irritate cells in the small intestine and/or in your brain.

Irritated cells send messages to the brain that instruct the body to feel nausea

Once irritated, cells in the small intestine send messages to the brain.

When irritated, cells in one area of the brain send messages to a different area of the brain.

Arrows pointing down to result of irritated cells causing nausea

Upon receiving these messages, the brain instructs the body to react through feelings of nausea and/or vomiting.

How SANCUSO helps prevent CINV

The Sancuso patch releases granisetron slowly and continuously until it's removed within 7 days

From the time that you apply the patch, SANCUSO slowly and continuously delivers granisetron through your skin and into your bloodstream until the patch is removed within 7 days.

Granisetron blocks the messages that trigger CINV

Granisetron blocks cells in the small intestine from sending messages to the brain that trigger CINV.

Granisetron blocks cells in one area of the brain from sending messages to a different area of the brain that triggers CINV.

Arrows leading to result of granisetron blocking signal that induces nausea

Because the brain does not receive these messages, feelings of nausea and/or vomiting are less likely to occur.

How do I get SANCUSO?

  1. Talk to your healthcare professional about whether this prescription medicine is right for you.
  2. Download and fill out this questionnaire to help guide your discussion.
  3. Either fill the prescription at your local pharmacy or have your doctor or nurse use our Patient RX Solutions program to get SANCUSO mailed directly to your home.
Patient Rx Solutions logo

Kyowa Kirin is committed to providing services and programs that help you gain access to and pay for the medications you need.

Patient RX Solutions offers reimbursement assistance, a copay assistance card,a and the SANCUSO patch replacement program.

Visit Patient RX Solutions

Learn More

aThis offer is not valid for prescriptions under Medicare (including Medicare Advantage, Part A, B, and D plans), Medicaid, VA, DOD, TRICARE, CHAMPUS, or other federal or state healthcare programs. Program managed by ConnectiveRx on behalf of Kyowa Kirin, Inc. The parties reserve the right to amend or end this program at any time. Product dispensed pursuant to program rules and federal and state laws. Void where prohibited or restricted by law.

Indication and Important Safety Information For Patients


SANCUSO® (granisetron transdermal system) is indicated for the prevention of nausea and vomiting in patients receiving moderately and/or highly emetogenic chemotherapy regimens of up to 5 consecutive days duration.


What is SANCUSO® (granisetron transdermal system)? 

SANCUSO is a prescription medicine used to prevent nausea and vomiting in patients receiving some types of chemotherapy treatment. SANCUSO is a skin patch that slowly releases the medicine contained in the adhesive (glue), through clean and intact skin areas into your bloodstream while you wear the patch. SANCUSO is for skin use only.

Who should not use SANCUSO?

Do not use SANCUSO if you are allergic to granisetron or any of the other ingredients in SANCUSO.

What should I tell my healthcare provider before using SANCUSO?

What should I avoid while using SANCUSO?

What are the possible side effects of SANCUSO?

The most common side effect of SANCUSO is constipation.

These are not all the possible side effects of SANCUSO. Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

For more information, ask your healthcare provider or pharmacist.

To report suspected side effects, contact Kyowa Kirin, Inc. at 1-800-SANCUSO or FDA at 1-800-FDA-1088 or

See full Patient Information for SANCUSO.